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Progesterone Therapy for Symptomatic Perimenopause

Learning Objectives

  1. Perimenopause, although characterized as a time of dropping estradiol involves chaotic estrogen levels that average >20% higher and intermittently are extremely high and ovulatory disturbances with decreasing progesterone levels.
  2. Perimenopause begins and is most symptomatic when cycles remain regular.
  3. Perimenopause is highly symptomatic for more than 20% of women--symptoms typically included heavy menstrual flow, night sweats, infertility, breast tenderness and sleep disturbances.
  4. Progesterone, because it normally counterbalances estradiol's actions, is effective treatment for heavy flow, probably night sweats, infertility and breast tenderness and definitely decreased anxiety and improves sleep.

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Jerilynn C. Prior MD, FRCPC, Professor of Medicine, Scientific Director, Centre for Menstrual Cycle and Ovulation Research (CeMCOR), UBC
Life Phase: 
Updated Date: 
September 30, 2010

Estrogen’s Storm Season: Stories of Perimenopause

Estrogen's Storm Season

by Dr. Jerilynn C Prior

New second edition available

Estrogen’s Storm Season is now available in BOTH print and eBook (Mobi and ePUB) versions!

All royalties are recieved in our Endowment fund (overseen by UBC) and support CeMCOR's research and future.

It is full of lively, realistic stories with which women can relate and evidence-based, empowering perimenopause information. It was a finalist in 2006 for the Independent Publisher Book Award in Health.

Purchase your ebook copy via our Amazon Kindle or
Google Play storefronts!

Paperback copies (with updated insert) still available here.

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